An additional module to the Europrobe allows dual optical detection by fluorescence and radio-nucleotide for to locate not only sentinel nodes but also ganglions. The combined use of these two detection methods reaches almost a 100% detection rate. This dual fluorescence and radioisotope detection method within one device is a worldwild exclusive.

ICG can be combined with a radioisotope for simultaneous administration to the patient.

The two indicators, ICG and radioisotope, can also be administered separately.

Opto-nuclear probes are designed to detect both isotopic markers and fluorescent markers (ICG).

Main features:

  • Optional add-on module
  • Allows dual Gamma and Fluorescence detection
  • Selection of the type of detection through a foot-switch
  • Simple and identical use to the Gamma procedure
  • Ready to use at normal light conditions
  • No specific installation required
  • Suitable for Indocyanine Green (ICG) detection
  • Improved discrimination and sensitivity


  • Tc 99m,
  • I125,
  • In111 – Sensitivity of fluorescence detection: <1nmol of ICG


  • Energy: 20 – 300 keV (Optimum efficiency: 20 – 170 keV)
  • Isotopes: 99mTc, 125l, 111ln – Sensitivity of fluorescence detection: <1nmol ICG
  • Medical grade stainless steel

Clinically confirmed

  • ICG – 99mTc-nanocolloid enables both preoperative SLN mapping and intraoperative SLN identification in melanoma patients
  • Optical identification of SLNs using the fluorescence signature of the hybrid indicator is better than SLN identification using blue dye.
  • ICG – 99mTc-nanocolloid improves the sensitivity of SLN detection to 98 %. Fluorescence imaging enabled intraoperative SLN identification in areas where acoustic gamma ray tracing is ineffective.
  • In other areas, fluorescence helped to pinpoint the location of SLNs with greater precision
  • Higher SLN identification rate: 99,8 %
  • A sharp decrease in the rate of false negative results:
    – 2.8 % for bimodal detection
    – 10 % for radioisotopes only

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