An additional module to the Europrobe allows dual optical detection by fluorescence and radio-nucleotide for to locate not only sentinel nodes but also ganglions. The combined use of these two detection methods reaches almost a 100% detection rate. This dual fluorescence and radioisotope detection method within one device is a worldwild exclusive.
ICG can be combined with a radioisotope for simultaneous administration to the patient.
The two indicators, ICG and radioisotope, can also be administered separately.
Opto-nuclear probes are designed to detect both isotopic markers and fluorescent markers (ICG).
Main features:
- Optional add-on module
- Allows dual Gamma and Fluorescence detection
- Selection of the type of detection through a foot-switch
- Simple and identical use to the Gamma procedure
- Ready to use at normal light conditions
- No specific installation required
- Suitable for Indocyanine Green (ICG) detection
- Improved discrimination and sensitivity
Isotopes:
- Tc 99m,
- I125,
- In111 – Sensitivity of fluorescence detection: <1nmol of ICG
Characteristics:
- Energy: 20 – 300 keV (Optimum efficiency: 20 – 170 keV)
- Isotopes: 99mTc, 125l, 111ln – Sensitivity of fluorescence detection: <1nmol ICG
- Medical grade stainless steel
Clinically confirmed
- ICG – 99mTc-nanocolloid enables both preoperative SLN mapping and intraoperative SLN identification in melanoma patients
- Optical identification of SLNs using the fluorescence signature of the hybrid indicator is better than SLN identification using blue dye.
- ICG – 99mTc-nanocolloid improves the sensitivity of SLN detection to 98 %. Fluorescence imaging enabled intraoperative SLN identification in areas where acoustic gamma ray tracing is ineffective.
- In other areas, fluorescence helped to pinpoint the location of SLNs with greater precision
- Higher SLN identification rate: 99,8 %
- A sharp decrease in the rate of false negative results:
– 2.8 % for bimodal detection
– 10 % for radioisotopes only